Found 70 matching trials
Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF PHASE1 The purpose of this study is to determine the safety and tolerability of or...
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Mayo Clinic Scottsdale Recruiting
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Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL PHASE2 Ph-like ALL is a recently recognized high-risk subgroup and the optimal the...
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Department of Hematology, Nanfang Hospital
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A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Classical Hodgkin's Lymphoma PHASE2 Phase II study to assess the efficacy of 6 cycles of oral JAK1/2 inhibitor ...
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UCL Louvain St Luc
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A Study of TQ05105 Tablets in Subjects With Hemophagocytic Lymphohistiocytosis(HLH) PHASE1 This is a phase I study of TQ05105 tablets in subjects with Hemophagocytic ...
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Beijing Friendship Hospital, Capital Medical University
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A Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor (Ruxolitinib; INBC018424) in Patients With Multiple Myeloma PHASE2 The purpose of this study was to determine clinical efficacy and safety of ...
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Multiple Locations
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Study of the Safety of PIM447 in Combination With Ruxolitinib (INC424) and LEE011 in Patients With Myelofibrosis PHASE1 This is a phase Ib study with the primary purpose is to estimate the MTD an...
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Novartis Investigative Site
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A Study of TQ05105 Tablets in Subjects With Myeloproliferative Neoplasms PHASE1 TQ05105 is a JAK2 inhibitors and can be used to treat JAK2 target-related d...
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West China Hospital ,Sichuan University
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Flonoltinib Maleate Oral Regimens in Patients With Myelofibrosis PHASE2 The goal of this clinical trial is to learn which of three different doses ...
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Multiple Locations
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Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis PHASE3 This is a global, multicenter, 2-part study to evaluate the efficacy and sa...
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Active Not Recruiting
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UAB Division of Hematology/Oncology
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To Evaluate the Effect of Food on the Pharmacokinetics of TQ05105 Tablets in Healthy Adult Subjects PHASE1 TQ05105 is a class 1 new drug with a new chemical structure developed by Ch...
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Affiliated Hospital of Changchun University of Traditional Chinese Medicine
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